Document 0056
 DOCN  M9490056
 TI    HIV-1 seroprevalence in an inner-city public hospital.
 DT    9411
 AU    Nagachinta T; Brown CP; Cheng F; Temple W; Kerndt PR; Janssen RS;
       Division of HIV/AIDS, Centers for Disease Control and Prevention,;
       Atlanta, GA.
 SO    J Natl Med Assoc. 1994 May;86(5):358-62. Unique Identifier : AIDSLINE
       MED/94322400
 AB    In a hospital-based seroprevalence survey for human immunodeficiency
       virus type 1 (HIV-1) infection, a stratified sampling method based on
       age and gender was used to collect 5429 blood samples at an inner-city
       hospital. Sentinel Hospital Surveillance System (SHSS) criteria
       developed by the Centers for Disease Control and Prevention were used to
       classify patient diagnoses into two categories by the likelihood of
       being associated with HIV-1 infection. The two categories were those
       with high likelihood of association with HIV-1 (SHSS-ineligible) and
       those with low likelihood of association with HIV-1 infection
       (SHSS-eligible). Of the 5429 blood samples, 4262 were SHSS-eligible and
       1167 were SHSS-ineligible. After personal identifies were removed,
       specimens were tested by ELISA and confirmed by Western blot analysis.
       The overall prevalence rate of HIV-1 infection was 0.98%. The
       seroprevalence rate was almost 2.6 times higher in high-association
       patients compared with low-association patients (1.89% versus 0.73%, P <
       .001). Results from this study indicate a high unsuspected HIV-1
       seroprevalence rate in a subpopulation (SHSS-eligible) considered to
       have diagnoses with low likelihood of association with HIV-1 infection.
       These patients may better approximate HIV-1 seroprevalence in the
       general population of the area served by the hospital than would a
       sample of all patients. Monitoring HIV-1 seroprevalence in the
       SHSS-eligible group will be a useful measure for community
       serosurveillance for HIV-1 infection.
 DE    Acquired Immunodeficiency Syndrome/DIAGNOSIS/*EPIDEMIOLOGY  Adolescence
       Adult  Age Factors  Aged  Child  Child, Preschool  Comparative Study
       Ethnic Groups/*STATISTICS & NUMER DATA  Female  Hospitals, Public
       Hospitals, Urban/*UTILIZATION  Human  *HIV Seroprevalence  Infant
       Infant, Newborn  Male  Middle Age  Pilot Projects  Prevalence  Sex
       Factors  Support, U.S. Gov't, P.H.S.  United States  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).